Different and conflicting epistemological orientations in Psychiatry. The italian so-called “Law 180” and the Mental Health Department actual organization. The Recovery process and the holistic view of people with mental illness that focuses on the person, not just their symptoms. Hallucinations: from psychopathology to neuroscientific and psychodinamic explanatory hypothesis. Dissociation, trauma, Addiction and Personality Disorders, and their common feature: the failure to modulate affects. The “minimal Self” construct and the Self-Disturbance’s role in the onset and course of Schizophrenia and other Psychosis. The right brain’s role both in the first emotional interactions with caregivers and then in the psychotherapeutic relationship. The Comprehensive and Integrated Treatment in Psychiatry (Need-Adapted Treatment, Multifamiliar Groups, individual Psychotherapy and CBT vs Psychodynamic Therapy different aims and indications). The “hidden subject” clinical model as a new way of understanding the psychopathology of both Personality Disorder and Addiction.