"G. d'Annunzio"
Nol
Students should know the laws of inheritance, the structure and functions of DNA and chromosomes, mutations and genetic diseases, the main chromosomal syndromes, the main molecular biology techniques and their applications.
The laws of inheritance, structure and functions of DNA and chromosomes, mutations and genetic diseases, major chromosomal syndromes. Main genetic syndromes of interest in orthoptics.
-Nucleic acids. DNA and RNA, structure, synthesis and duplication. Chromatin, heterochromatin, euchromatin. - Gene structure. Protein synthesis, genetic code, regulation of gene expression. -Cytogenetics. Notes on cytogenetic techniques, normal human karyotype. - Chromosomal abnormalities. Numerical and structural alterations of chromosomes. Main chromosomal syndromes. Chromosomal alterations and spontaneous abortions. - Prenatal diagnosis. - Mendel laws. Autosomal dominant and recessive inheritance, heterosomal inheritance, mitochondrial inheritance. Polygenic inheritance. Particularity of the Mendel laws. -Mutations. Point mutations, frameshift, dynamics. Chemical and physical mutagens. -Main molecular biology techniques and their applications. Gene cloning. - Oncogens and oncosuppressors.
Russell, Hertz, McMillian. Elementi di Genetica. Edises.
Frontal lessons
Oral
Slides will be provided to the students
