The program is divided into the following points:
a) acquisition of the basic elements relating to the physiopathology of blood and its
components. Clinical evaluation of anemias and study of correlated parameters. Analyses
leukemia and lymphoma clinics and staging.
b) Pathophysiology of hemostasis. Analysis of the components of the coagulation cascade.
Clinical evaluations of coagulative-deficiency states. Deficiency of factors and them
role in hemorrhagic states.
c) Immunological investigation parameters. Diagnostic-clinical evaluation
of inflammation and role of cellular components. Immunophenotyping and its
application in the main cases of immunodeficiency and neoplastic induction.
Study of autoimmunity and description of the main autoimmune syndromes: disease
celiac, reactive pathologies of the gastroenteric system (M. of Chron, rectocolitis
ulcerative), Sijogren's syndrome, SLE, Rheumatoid arthritis, scleroderma
d) Tumor serological markers. Analysis of the molecular alterations of the principals
genes in the pathogenic processes of tumors. Pathogenesis of gastrointestinal tumors.
Principles of predictive medicine and study of prediction markers for the main ones
familial oncological syndromes: breast and ovarian cancer, HNPCC, tumors
hereditary thyroid disease, retinoblastoma, Li-Fraumeni syndrome
e) Principles of pharmacogenetics and pharmacogenomics. Response prediction
therapeutics in tumors. Presentation of the main application protocols
diagnostic-molecular in the chemotherapeutic orientation of neoplasms