Microscopic anatomy of the tissues
- Epithelial tissue: epithelia, exocrine and endocrine glands.
- Connective tissue, cartilage, bone tissue, haematopoietic tissue, blood, limph, lymphoid tissue.
- Muscle tissue
- Nervous tissue
Endocrine apparatus
Osteoarticular apparatus: skull, vertebral column, rib cage, pelvis. Classification and structure of joints.
Muscular apparatus: Diaphragm, muscles of the anterlateral abdominal wall. Inguinal duct. Urogenital diaphgram.
Blood circulatory apparatus: heart, pulmonary and system circulations. Inferior and superior vena cava, portal vein, azygos veins.
Lymphatic system: lymphatic vessel structure, thoracic duct, thymus, spleen and lymph nodes.
Peritoneum.
Respiratory apparatus: nasal cavity, pharynx, larynx, trachea, bronchi, lungs. Pleura. Alveolus.
Excretory apparatus: kydneys, ureters, bladder, male and female uretra, nephron.
Digestive apparatus: oral cavity, main salivary glands, pharynx, oesophagus, stomach, small and large intestine, anal canal. Liver, pancreas and gall bladder.
Male reproductive apparatus: testis, epididymis, vas deferens, prostate gland, seminal vesicles.
Female reproductive apparatus: ovary, fallopian tubes, ovary, uterus.
Human embryology: male and female gametogenesis, fecundation, segmentation, gastrulation, embryo development.
Nervous system: central nervous system, spinal cord, enceflaic nerve nuclei, reticular formation. Encefalic circulation. Meninges and liquoral circulation. Nods on spinal and cranic nerves. Lymbic system, autonomous nervous system.
Composition of living matter: Biological macromolecules: carbohydrates, lipids, proteins, nucleic acids .
Living organisms: Characteristics of living organisms. The kingdoms of living organisms. Differences between prokaryotes and eukaryotes. Virus: structure, replication and types. Viroids and prions.
Components of the prokaryotic cell: cell wall, flagella, cell membrane, cytoplasm, genetic material. Bacteria: composition , movement, reproduction ( binary fission, transformation, conjugation, transduction), metabolism.
Components of the eukaryotic cell: cytoplasmic organelles (rough and smooth endoplasmic reticulum, ribosomes, Golgi apparatus, mitochondria, lysosomes, peroxisomes) and the nucleus (nuclear pores, nucleolus and chromatin). Cytoskeleton: microtubules, microfilaments and intermediate filaments. Cell junctions (desmosomes, tight junctions, gap junctions).
Structure and function of biological membranes. Cell-environment interactions. Mechanisms of transport across the membrane: simple and facilitated diffusion, active transport and passive (sodium-potassium pump), exocytosis and endocytosis. Receptor-mediated endocytosis. Mechanism of action of steroid hormones and peptide hormones (second messengers and signal transduction). DNA double-helix structure and replication. Various levels of organization of DNA in the cell: nuclear chromatin and chromosome structure. Eukaryotic gene structure. RNA: structure, function and types. Transcription and RNA processing. Genetic code. Protein synthesis. Gene regulation in prokaryotes (lactose operon and tryptophan operon). Gene regulation in eukaryotes. Genes and development. Cell differentiation and nuclear equivalence. The genetic control of development.
Energy metabolism:
The cell and energy. The flow of energy. Metabolic reactions. Role of ATP and cellular work. Energy metabolism. Cellular respiration: glycolysis, Krebs cycle and oxidative phosphorylation. Photosynthesis.
Elements of Genetics: Cell cycle and its regulation. Mitosis and Meiosis stages and differences. Mendel's laws: dominance, segregation of alleles, independent assortment of alleles. Concept of the gene, locus, allele, genotype and phenotype. Extensions of Mendelian genetics. Mode of transmission of characters (autosomal dominant, recessive, X-linked ).
Ecosystems: population and community ecology. Ecosystems and the biosphere.