PRINCIPLES OF GENERAL PHARMACOLOGY: definition of drug; generic drugs and medicinal specialties; overview of pharmacovigilance.
Pharmacokinetic elements: main routes of drug administration (outline of the main pharmaceutical forms and the correct administration of drugs); absorption, distribution, biotransformation and excretion of drugs; bioavailability; therapeutic range; plasma half-life; dose-effect curves (DE50, DL50, DT50); therapeutic index.
Principles of pharmacogenetics and variability of the pharmacological response.
Elements of Pharmacodynamics: drug-receptor interactions; main receptor classes; main signal transduction pathways; receptor agonists and antagonists; definition of power and maximum efficacy of a drug; receptor desensitization, upregulation, and downregulation.
PRINCIPLES OF SPECIAL PHARMACOLOGY
Pharmacological therapy of inflammation. Glucocorticoids and non-steroidal anti-inflammatory drugs (NSAIDs).
Drugs used in the treatment of bronchial asthma (essential lines on the most common drugs).
Drugs of more common use for the control of gastric acidity and for the treatment of peptic ulcer.
Drugs used in the treatment of arterial hypertension (essential lines on drugs of most common use).
Drugs used in the treatment of heart failure (essential lines on drugs of most common use).
Drugs active on the central nervous system with particular reference to the use of benzodiazepines
Antibacterial chemotherapy: Classification of antimicrobial drugs. Factors that determine the susceptibility and resistance of microorganisms to the most common antimicrobial drugs (Penicillins, Cephalosporins, Macrolides, Fluoroquinolones).