NEPHROLOGY

Course Sheet

Course code:

IN21B22D

Academic Year of enrolment:

2022

Year of supply:

2023/2024

Divisions:

CANALE A

Type of Course:

Characterising

Degree:

Course of 1st Cycle Degree in NURSING

Disciplinary Sector:

Nephrology

Is part of:

NEPHROLOGY

Location:

PESCARA

Credits:

Programme Year:

Professor and Collaborators:

SIROLLI Vittorio

Cycle:

First semester

Obligatory attendance:

Yes

Hours of classroom activity:

Individual study hours:

Prerequisites:

anatomy and histology of the genitourinary system;
- general concepts of physiology of the genitourinary system;
- general concepts of imaging of the genitourinary system;
- general notions regarding inflammatory, infectious, and immunological
processes.

Objectives

The teaching contributes to the realization of the educational objective of
the School of Medicine by providing students with knowledge about signs
and symptoms, diagnostic procedures, and therapeutic indications in
kidney diseases.
Expected learning outcomes
At the end of teaching the students will be able to:
a) with reference to the symptom-signs proteinuria, haematuria, oliguria,
polyuria, and peripheral edema:
to illustrate the single pathophysiological mechanisms;
to list the clinical significance and the main causes;
to plan a correct diagnostic procedure.
b) To interpret in a physiological and diagnostic key the possible resuls of
the urine test.
c) To specify indications and controindications, complications, costs,
reliability of the main specialized diagnostic procedures:
- renal function test
- urine colture
- renal biopsy
- diagnostic imaging
- laboratory parameters.
d) With reference to the systematic nosography:
- To know, on the basis of epidemiological information, which are the
most frequent pathologies affecting the urinary system.
- To differentiate and interpret the pathophysiological elements of clinical
semeiology in order to correctly frame the pathogenesis.
- To specify the pathogenic role of the main risk factors.
- To be able to analyze clinical and instrumental data to make a correct
diagnosis and set up a therapeutic schema.

Contents

1) Diagnostic use of signs and nephro-urological symptoms interpreted in
relation to their physiopathogenesis.
2) Pathophysiological, laboratory and instrumental diagnostic procedures,
and their indications in nephrology disorders.
3) Systematic nosology of the main nephrological diseases.
4) Basic concepts concerning the criteria and indications of renal
replacement therapy.
5) Essential concepts concerning therapeutic indications in the pathology
of the nephropatic patient.

Extended Syllabus

Modalità di verifica dell'apprendimento MOD_VER_APPR Sì Colloquio orale, voto in trentesimi Oral interview, vote in thirtieths
Programma esteso PROGR_EST Sì Argomenti di lezione:
ELEMENTI FISIOPATOLOGICI E DIAGNOSTICI DELLE NEFROPATIE
Valutazione dell’esame urine; valutazione della funzione renale; segni e
sintomi delle nefropatie; indagini strumentali in nefrologia; biopsia renale.
NEFROPATIE GLOMERULARI
Classificazione; sindromi glomerulari cliniche; riferimenti di sintesi sulla
eziopatogenesi e sui principali quadri anatomo-clinici; nefropatia
diabetica; criteri generali di terapia.
NEFROPATIE VASCOLARI
Classificazione; nefropatia ipertensiva; ipertensione nefrovascolare;
nefropatia ischemica.
NEFROPATIE INTERSTIZIALI
Classificazione; pielonefriti; malattie cistiche renali.
INSUFFICIENZA RENALE ACUTA
Classificazione; etiologia, patogenesi, fisiopatologia, sintomatologia,
diagnostica clinica e strumentale delle varie forme di insufficienza renale
acuta; criteri generali di terapia medica.
INSUFFICIENZA RENALE CRONICA
Classificazione in 5 stadi; etiologia, epidemiologia, fisiopatologia,
sintomatologia, diagnostica, terapia medica atta ad antagonizzare la
progressione della malattia e a trattare le complicanze ad essa associate.
TERAPIA SOSTITUTIVA DELLA UREMIA CRONICA
Inizio e scelta della terapia sostitutiva artificiale cronica; caratteristiche
principali della emodialisi e della dialisi peritoneale; idoneità al trapianto Lesson topics:
PATHOPHYSIOLOGICAL AND DIAGNOSTIC ELEMENTS OF KIDNEY DISEASE
Evaluation of urine examination and of renal function; signs and
symptoms of kidney diseases; instrumental procedures; kidney biopsy.
GLOMERULAR NEPHROPATHY
Classification; clinical glomerular syndromes; main notions on
pathogenesis and morphology; diabetic nephropathy; general principles
of therapy.
VASCULAR NEPHROPATHY
Classification; hypertensive nephropathy; renovascular hypertensione;
ischemic nephropathy.
INTERSTITIAL NEPHROPATHY
Classification; pyelonephritis; cistic diseases of kidney.
ACUTE RENAL FAILURE
Classification; etiology, pathogenesis, pathophysiology, symptoms,
diagnostic procedures in acute renal failure; generasl principles of
medical therapy.
CHRONIC RENAL FAILURE
Classification; etiology, epidemiology, pathophysiology, symptoms,
diagnostics, medical therapy aiming to show down the progression of the
disease and to treat complications of the disease.
REPLACEMENT THERAPY OF CHRONIC UREMIA
Start and choice of chronic renal replacement therapy; main features of
hemodialysis and peritoneal dialysis; main characteristics of kidney
transplantation.

Recommended Bibliography

- Albertazzi Porena, Malattie del Rene, delle Vie Urinarie e dell’Apparato
Genitale Maschile, Piccin Editore, 2017
- V. Bonomini, Nefrologia Clinica, Esculapio Editore, 1990
- G. Garibotto, R. Pontremoli, Manuale di Nefrologia – II Edizione, Edizioni
Minerva Medica, 2017

Teaching Methods

Classroom lessons for all students
Exercises in small groups during the frequency of the Nephrology
Department.

Evaluation methods

Verification of learning:

Oral interview, vote in thirtieths

Contacts/More Information

Students are received at the Department of Nephrology Clinic, preferably
on Tuesday and Thursday (h 12-13).
Optional activities are the following elective activities:
- Current events and perspectives in renal replacement therapy (Prof.
Mario Bonomini)
The activity aims to provide an update on the current status and on the
prospects also experimental in artificial replacement therapy (dialysis)
and natural (transplant) of chronic uremia.
- Multidisciplinarity of therapeutic apheresis techniques (Dr. Vittorio
Sirolli)
The activity aims to provide an in depth analysis of the various apheretic
methods currently available to us and the therapeutic indications for their
correct use.

Università degli Studi
"G. d'Annunzio"

Chieti - Pescara

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