Research into the regulatory references of the nursing profession. Research training levels. Research, nursing research and research methodology. The research process: a) from problem identification to question/hypothesis; b) the literature review: clarifications on terminology (Literature Review and Systematic Review), purposes, structure and drafting; c) presentation of the main quantitative and qualitative research designs and selection in accordance with the aims and objectives of the study; d) sampling techniques and data collection tools, overview of the use of the questionnaire, observation and interviews. The concepts of reliability and validity. The “Evidence phenomenon”. Ethical issues related to nursing research and research.